Nurse-led education

Escalating observations and prompting an intervention – why speed is important

Michelle Kenyon, Post-BMT Clinical Nurse Specialist at King’s College Hospital, on escalating observations, prompting interventions, and why speed is so vital when it comes to identifying VOD.


Diagnosis and severity grading Risk assessment and monitoring


Adverse events should be reported. Reporting forms and information for the UK can be found at:

For Ireland, reporting forms and information can be found at:

Adverse events should also be reported to Jazz Pharmaceuticals at:

Defitelio® is indicated for the treatment of severe hepatic veno-occlusive disease (VOD) also known as sinusoidal obstruction syndrome (SOS) in haematopoietic stem-cell transplantation (HSCT) therapy. It is indicated in adults and in adolescents, children and infants over 1 month of age.