Consultant-led education

Monitoring for VOD: Best practice from University Hospital Birmingham

Dr Manos Nikolousis describes the monitoring practice at his trust, as well as the value of a 24-hour blood and marrow transplantation chart in maintaining best practice.


Risk assessment and monitoring


Adverse events should be reported. Reporting forms and information for the UK can be found at:

For Ireland, reporting forms and information can be found at:

Adverse events should also be reported to Jazz Pharmaceuticals at:

Defitelio® is indicated for the treatment of severe hepatic veno-occlusive disease (VOD) also known as sinusoidal obstruction syndrome (SOS) in haematopoietic stem-cell transplantation (HSCT) therapy. It is indicated in adults and in adolescents, children and infants over 1 month of age.